Chopra made his Test debut in Ahmedabad against New Zealand in late 2003 as India sought to find an opening partner for his Delhi teammate Virender Sehwag. Chopra’s international career started well, scoring two half-centuries against New Zealand during 2003/04 in the second Test in Mohali. On the 2003–04 tour to Australia, he featured in many solid partnerships with Virender Sehwag, including two century opening partnerships in Melbourne and Sydney. Chopra’s work in seeing off the new ball saw him credited with the large scores that India accumulated in that series when middle-order batsmen Rahul Dravid, V. V. S. Laxman, Sachin Tendulkar and Sourav Ganguly regularly compiled large centuries.

Chopra was reintroduced as Sehwag’s partner in the 2004 Border-Gavaskar Trophy after Tendulkar was injured for the First Test in Bangalore. However, a heavy loss saw Chopra axed for the following match in Chennai upon Tendulkar’s return, with Yuvraj elevated to opening the innings. Yuvraj also struggled, and Chopra was recalled for the Third Test in Nagpur. However, a double failure by Chopra, as Australia won a series in India for the first time in 35 years, saw him dropped for the last time, after his career average gradually decreased, however, from 46.25 to only 23. Chopra was replaced by Delhi teammate Gautam Gambhir, and was overtaken by Gambhir and Wasim Jaffer in the race to partner Sehwag in the Test side. Due to his low scoring rate, he was not considered for One Day Internationals.

In September 2008, Aakash played for Delhi in the Nissar Trophy against SNGPL (winners of Quaid-i-Azam Trophy from Pakistan) and scored 4 and 197 for Delhi. The match was drawn but SNGPL won the trophy on first-innings lead. After representing Delhi for a long time, Chopra joined Rajasthan as a guest player in Ranji Plate division. He helped Rajasthan to become the first Plate division team to win the Ranji Trophy followed by another Ranji trophy win in 2010–2011 season. He has won three Ranji titles in total—one with Delhi and two with Rajasthan. He’s one of the few Indian cricketers who have scored over 8,000 First-Class runs.

In 2009 Chopra released Beyond the Blues: A First-Class Season Like No Other, a diary of Chopra’s 2007–08 domestic season. It was published by Harper Collins. It was critically acclaimed and Suresh Menon of Cricinfo wrote that it was “the best book written by an Indian Test cricketer”. In November 2011, his second book was published by Harper Collins titled Out of the Blue, about Rajasthan’s victory in the Ranji Trophy. He went on to write two more books—The Insider with Espn Cricinfo in 2015 and Numbers Do Lie with Impact Index in 2017. Harper Collins has published all his work thus far.

In May 2020, Aakash Chopra signed as a commentator with popular mobile cricket game World Cricket Championship to lend his voice for the upcoming WCC3 game. Aakash Chopra was the first commentator to sign as commentator with a digital game platform.