Sele began his third pro season with Triple-A Pawtucket and pitched a one-hit 7-inning shutout in his first Triple-A start on April 10 at Columbus and was 4-0, 1.98 in final 6 starts. He was purchased from Pawtucket on June 22, 1993.
On September 6, 1993 while pitching against the White Sox in Chicago, Sele was involved in one of baseball's more memorable fights. After two consecutive inside pitches, George Bell charged the mound. Sele, seeming to have a plan, did not move until Bell was feet from him, about to throw a punch. At the last second, Sele ducked to his left as Bell threw the punch and the burly Mo Vaughn, having rushed to the mound from first base, ran into Bell. Bell flipped backwards, crashing to the ground as both of the benches emptied and the teams made their way to the mound [1].