On February 16, 2019, Escobar signed a minor-league contract with the Baltimore Orioles that included an invite to spring training. On March 20, 2019, Escobar was granted his outright release from the Orioles.
On March 22, 2019, Escobar signed a minor league deal with the Chicago White Sox. He was released on August 2, 2019.
On October 30, 2019, Escobar signed with the Tokyo Yakult Swallows of Nippon Professional Baseball (NPB). On January 31, 2020, he held press conference with Gabriel Ynoa and Matt Koch.
On December 19, 2019, Escobar made his NPB debut. On July 15, 2020, he hit his first NPB career home run.