Alexis Kaufman was born on August 9, 1991, in Columbus, Ohio. She has been involved in sports since the age of five, competing in track, kickboxing, softball, and gymnastics. She was also a cheerleader at Hilliard Davidson High School and reached Division I status at the University of Akron. She spent time in competitive fitness competitions, and has competed in the Arnold Classic. At the age of 15, she suffered from a life-threatening eating disorder, but turning to fitness competitions helped her overcome it.

Having no prior wrestling training, Kaufman was signed by WWE in May 2013 and reported to WWE’s developmental territory NXT. On the July 24 episode of NXT (which was taped on June 20), she made her first televised appearance, congratulating the inaugural NXT Women’s Champion Paige. In August, she was added to WWE.com’s NXT roster page and assigned the ring name Alexa Bliss. She acted as an unnamed ring announcer for the November 20 episode of NXT. Her first televised appearance on the main roster came at WrestleMania XXX on April 6, 2014, when she played a part in Triple H’s entrance. She made her televised in-ring debut on the May 8 episode of NXT, playing a glitter fairy gimmick, competing in a tournament for the vacant NXT Women’s Championship. She defeated former Divas Champion Alicia Fox in the first round, but lost to Charlotte in the semi-finals.

On July 24, 2017, it was announced that Bliss would be joining the seventh season of Total Divas. She is also a recurring guest on Xavier Woods’ YouTube channel UpUpDownDown, where she goes by the nickname Miss Bliss. In November 2019, she defeated Cesaro, Rusev, and The Miz in the finals of a Brawlhalla tournament to win Cesaro’s UpUpDownDown Championship, but she immediately lost the title to Tyler Breeze in Saturday Night Slam Masters.

On February 25, 2018, at Elimination Chamber, Bliss won the inaugural women’s elimination chamber match, after she successfully retaining her title. In parallel to her activities as a singles wrestler, she took a part of the Mixed Match Challenge tournament with Braun Strowman as her partner, and the duo was able to qualify to the semi-finals of the tournament, where they were defeated by the eventual winners Asuka and The Miz. On April 8 at WrestleMania 34, Bliss lost the title to Nia Jax, ending her reign at 223 days. On May 6 at Backlash, Bliss invoked her rematch clause and challenged Nia Jax for the title, however, she was unsuccessful and suffered a shoulder injury during the match.

On the January 7, 2019 episode of Raw, Bliss debuted an interview segment titled A Moment of Bliss, where she interviewed various guests as the segment’s host. At Royal Rumble on January 27, after a nearly five month in-ring hiatus, Bliss competed in her first women’s Royal Rumble match, lasting 12 minutes and eliminating Ember Moon and Sonya Deville before she was eliminated by Bayley and Carmella. In April, Bliss hosted the WrestleMania 35 event. The following night on Raw, Bliss defeated Bayley in her first singles match since her hiatus from in-ring competition in late 2018. At The Shield’s Final Chapter event, Bliss teamed up with Lacey Evans to defeat Dana Brooke and Nikki Cross in a dark match. Shortly thereafter, Bliss was announced as a participant of the annual Money in the Bank ladder match at the namesake pay-per-view. However, she was not medically cleared to compete in time for the event and therefore removed from the match.

Kaufman was previously engaged to Australian wrestler Buddy Murphy. They ended their engagement in 2018, but remain friends. As of February 2020, Kaufman has been dating singer Ryan Cabrera.

On the August 5 episode of Raw, Bliss and Cross would win the WWE Women’s Tag Team Championship from The IIconics in a fatal four-way tag team elimination match also involving The Kabuki Warriors (Asuka and Kairi Sane), and Fire and Desire (Mandy Rose and Sonya Deville). Bliss and Cross retained their titles against Fire and Desire at Clash of Champions. At the Hell in a Cell on October 6, they lost the titles to The Kabuki Warriors after Asuka spat green mist in Cross’ face, thus turning them face in the process. This would be Bliss’ first time as a face on the main roster. Although drafted separately instead of as a team during the 2019 Draft, Bliss and Cross remained on the Raw brand, but the team was then traded to the SmackDown brand. At Starrcade, Bliss and Cross competed in a fatal four way tag team match for the Women’s Tag Team Championship, but the match was won by defending champions The Kabuki Warriors. At the Royal Rumble on January 26, 2020, Bliss entered the namesake match at number 1, lasting 27 minutes and eliminating Kairi Sane, Mia Yim, and Chelsea Green, but was eliminated by Bianca Belair.

In early 2020, Bliss appeared in the music video for a song by Bowling for Soup, having previously cited them as her favorite band.

On June 23, 2020, Bliss confirmed her long rumored WWE podcast, which is titled Uncool with Alexa Bliss and debuted on September 22, 2020.