She was the original “Trina” (Marvin’s ex-wife) in William Finn’s March of the Falsettos and In Trousers (Playwrights Horizons). She also did vocal orchestrations for both shows. She played “Miss Drumgoole” in Todd Rundgren’s adaptation of Joe Orton’s Up Against It (New York Shakespeare Festival), “Uta” in Charles Busch and Rusty Magee’s The Green Heart (Manhattan Theatre Club), “Connie”/”Petula”/”Brenda” in Beehive at the Village Gate, and “Marion Ames” in Swingtime Canteen. In 1988, she appeared on Broadway in Romance/Romance, a musical starring herself and Quantum Leap star, Scott Bakula. For her dual-role as Josefine/Monica, Fraser received her first Tony Award Nomination. In 1991, Fraser appeared in The Secret Garden, a musical based on the children’s story by Frances Hodgson Burnett. For originating the role of Martha, Fraser earned a second Tony Award Nomination. The Secret Garden also featured Mandy Patinkin, Daisy Eagan, John Cameron Mitchell and Rebecca Luker. Fraser stars in the one-woman show A Tennessee Williams Songbook conceived and directed by David Kaplan with musical direction by Allison Leyton-Brown. The show premiered at The Tennessee Williams Festival in Williams’ birthplace of Columbus, Mississippi and went on to great acclaim at the annual Provincetown Tennessee Williams Festival. An original cast album titled Tennessee Williams: Words and Music was released on Sh-K-Boom Records in 2013.

In 2004, Fraser sang the National Anthem at Fenway Park.

In 2009, Arthur Laurents cast Fraser in an original play, Come Back, Come Back, Wherever You Are which premiered at the George Street Playhouse. The play was directed by Laurents himself and featured Tony-winning actress, Shirley Knight. Also with Knight, Fraser appeared in the 2012 world premiere of Tennessee Williams’ final full-length play In Masks Outrageous and Austere.

In 2010, playwright and performer Charles Busch cast Fraser in his new comedy, The Divine Sister, a play satirizes the cinematic portrayal of nuns. Fraser played Sister Walburga. Fraser then originated the role of Arsinoe in David Ives’ comedy The School For Lies at Classic Stage Company.

Fraser graduated summa cum laude in spring 2010 from Fordham University, where she now teaches a musical theatre course.

On December 16, 2013, Fraser joined the First National Tour of Wicked in the role of Madame Morrible.

In 2015, Fraser appeared in four episodes of the Showtime television series Happyish as both Ma Keebler and Boots.