In the 2010s, she returned to television and worked on a series of eponymous interview projects. In 2011, it was announced that de Cadenet would be the host of a new television interview series called The Conversation with Amanda de Cadenet, airing on the Lifetime Channel, with Demi Moore as a co-executive producer. On the show, de Cadenet has interviewed female guests such as Hillary Clinton, Lady Gaga, Portia de Rossi, Rita Wilson, Gwyneth Paltrow, Zoe Saldana and Jane Fonda. During the production of The Conversation, she developed a second show with Lifetime, a weekly late-night television talk show featuring de Cadenet entitled, Undone with @AmandadeCadenet. The show ran for six episodes in 2014. In 2018, she worked with Showtime to develope a pilot for a half-hour weekly news-magazine show tentatively titled Now What With Amanda de Cadenet. The show did not air. In 2019, she developed a ten-episode spin-off podcast of The Conversation in partnership with Spotify.