In 2011, the White House announced the updated Strategy for American Innovation which was aimed at innovating a number of areas of the federal government. As part of President Obama's goal to "win the future," Chopra implemented a number of new programs focused on education, research, and infrastructure.
Startup America, launched in 2011, is a White House program aimed at spurring innovation through entrepreneurship. Chopra helped drive the Startup America effort worked to improve access to startup capital, reduce barriers to entry, connect entrepreneurs with mentors, and create new market opportunities in health care, clean energy and education. Along with the White House initiatives, the Startup America Partnership was created as an independent alliance of private sector leaders.