Though her repertoire includes many classical works, Mutter is particularly known for her performances of contemporary music. Several pieces have been specially written for or dedicated to her, including Henri Dutilleux's Sur le même accord, Krzysztof Penderecki's Second Violin Concerto, Witold Lutosławski's Chain 2 and the orchestral version of Partita, and Wolfgang Rihm's Gesungene Zeit ("Time Chant"), Lichtes Spiel, and Dyade. In August 2007, she premiered Sofia Gubaidulina's Violin Concerto No. 2 "In tempus praesens." She has received various prizes, including several Grammys.