On 4 July 2007, Hamer signed a new one-year contract to keep him at Reading until the end of the 2007–08 season. He joined Brentford in an initial one-month loan deal on 11 August 2007, which was subsequently extended to 14 October 2007. Brentford re-signed Hamer in an emergency loan deal on 1 January 2008, following an injury to their first choice ‘keeper, Simon Brown. On 28 January 2008, his loan was extended to the end of the 2007–08 season.

On 18 June 2009, Hamer signed a new two-year contract and was expected to jostle with Adam Federici for the Number 1 jersey. On 31 August, Hamer was loaned back to Brentford for a fourth spell with the Bees.

On 18 January 2011, Hamer joined League One side Exeter City on a three-month loan deal. Hamer made his Exeter City debut against Walsall on 22 January 2011.

On 1 August 2011, Hamer joined Charlton Athletic on a three-year contract and was immediately handed the number one jersey. He made his debut on 23 August 2011 against his former club Reading in the League Cup first round and helped Charlton to a 2 – 1 win. After some initial nervous performances he cemented his place in the team, making crucial saves throughout Charlton’s title winning League One campaign. He clinched promotion to the Championship with Chris Powell’s side in April 2012, with a 1 – 0 win over Carlisle United and continued to play regularly for the Addicks during the 2012–13 season. A series of injuries resulted in hamer playing fewer matches in the 2013–14 season.

After several weeks of strong speculation about Hamer’s move to Leicester City, it was finally confirmed on 22 May 2014, by Hamer himself on social media. Hamer says he made the move to the newly promoted Foxes for the chance to play Premier League football. He made his debut in a 1–0 defeat at home to Shrewsbury Town in a League Cup second round tie. Following an injury to Kasper Schmeichel whilst on international duty, Hamer made his Premier League debut on 13 September, putting in a very good performance and keeping a clean sheet as Leicester secured a 1–0 win at Stoke City, their first victory since returning to the Premier League.

He played his second game for Leicester against Premier League champions, Manchester City in a 0–1 home defeat on 13 December. After playing 7 games for Leicester, Hamer lost his place when on 6 January 2015, Leicester signed experienced goalkeeper Mark Schwarzer from Chelsea to help cover for the injured Kasper Schmeichel. In the 2016–17 season, Hamer started Leicester’s sixth Champions League group game, giving him his Champions League debut. Leicester lost 5–0 to FC Porto.

On 25 July 2015, Hamer joined Championship side Nottingham Forest on a season-long loan deal. However, he returned to Leicester on 4 August after the loan was cut short due to Nottingham Forest’s financial issues.

On 11 August 2015, Hamer joined Championship side Bristol City on season-long loan deal. However, he returned to Leicester City on 17 November 2015 after making only five appearances for the club.

On 1 June 2018, Huddersfield Town announced the signing of Hamer on a free transfer once his contract ended on 1 July.

On 8 August 2019, Hamer joined Derby County on loan for the 2019–20 season as back up for Kelle Roos. He made his debut and kept a clean sheet in a 1–0 win at Scunthorpe United in the EFL Cup first round. On 30 November 2019, Hamer made his league debut and thereafter became first choice keeper.