Shephard’s career took off in 1998, when he began hosting Channel 4 spin-off show The Bigger Breakfast, alongside fellow presenters including Josie D’Arby, Melanie Sykes and Dermot O’Leary. That same year, Shephard became the first presenter of T4’s teen strand on Channel 4, which launched on 25 October 1998. He also presented Control Freaks for the channel in 1998.

Shephard joined the long-running programme GMTV in 2000 where he presented Entertainment Today alongside Jenni Falconer. He also became the main relief presenter for GMTV Today. Due to the departure of Eamonn Holmes in April 2005, Shephard became Fiona Phillips’ co-host on GMTV Today, presenting on Mondays, Tuesdays and alternate Wednesdays. He continued to present Entertainment Today, but began to share duties with Michael Underwood. When GMTV relaunched in January 2009, his main co-host became Kate Garraway, presenting on Monday, Tuesday and alternate Wednesdays.

Between 2004 and 2006, Shephard presented the first three series of ITV2 spin-off programme The Xtra Factor, whilst Kate Thornton hosted the main show on ITV While hosting the show, Shephard also starred in The Xtra Factor – Battle of the Stars. He left the show after three series after missing out on the main presenting role (which went to Dermot O’Leary after the departure of original host Kate Thornton); he was replaced by Fearne Cotton.

Shephard appeared in the 2004 TV film A Bear’s Christmas Tail as a carol singer. He also appeared in Harry Potter and the Half-Blood Prince in 2009. He played the role of Diagon Alley Father, but was uncredited. Shepherd narrated and presented Walt Disney World in Orlando, Florida, for UK and US Stacey J Aswad. In 2009, Shephard starred in an episode of Bookaboo on CITV. In 2012, Ben was a studio host for the London 2012 Olympic Games, and Paralympic Games, which was only made available to view in the Olympic park. At this time, he also acted as a stadium commentator, where he introduced all of the action in the main arena, and he also interviewed celebrity guests.

Shephard married Annie Perks on 25 March 2004, and the couple have two sons.

Between 2005 and 2011, Shephard was a stand-in presenter on This Morning, covering for regular presenter Phillip Schofield. In 2014, Ben was a stand-in presenter on This Morning Summer, co-hosting one episode alongside Ruth Langsford. Since 2015, he has been a regular stand-in presenter for Schofield and Eamonn Holmes.

In 2006, Shephard co-presented reality singing contest Soapstar Superstar alongside Fern Britton. The programme returned the following year in 2007, without Shephard as the host. In 2007, Shephard co-hosted Dancing on Ice Exclusive, a spin-off series which aired on ITV.

In 2006, Shephard was a presenter on Magic Radio station. He presented a Saturday breakfast programme. He returned to radio in 2008, where he presented a Monday evening show on Heat Radio.

In 2006, 2008, 2010, 2012, 2014, 2016, and 2019, Shephard played for England in Soccer Aid which aired live on ITV. The Soccer Aid events raise money for the Unicef charity. In 2016 he was red carded for a “cynical foul” on Dimitar Berbatov. Shephard did not take part in 2018’s Soccer Aid due to an injury. Instead, he was appointed as England Coach for that year’s Soccer Aid. Shephard did not take part in 2020’s Soccer Aid.

In the earlier 2000s, Shephard was a regular presenter of BBC Choice’s EastEnders Revealed program. In 2007, Shephard presented the BBC entertainment series DanceX with Strictly Come Dancing judges Arlene Phillips and Bruno Tonioli on the panel.

In 2008, Shephard co-presented Who Dares, Sings! with Denise van Outen. The series received reasonable viewing figures, achieving an average of 3.58 million viewers.

Between 2008 and 2009, Shephard presented the National Lottery game show 1 vs. 100, taking over from Dermot O’Leary.

Shephard has hosted numerous music specials on the channel, celebrating some of Britain’s best-loved musicians. These shows were Rod Stewart: One Night Only, which aired on 5 December 2009 and Phil Collins: One Night Only, which aired the following year on 18 September 2010.

In 2009, ITV revived the classic game show The Krypton Factor, with Shephard chosen to present the new series. Following the success of the first series in 2009, he was asked to present a second series the following year. In 2010, Shephard co-presented a short-lived show called Dancing on Ice Friday alongside Coleen Nolan. The show was a spin-off from the main Dancing on Ice show.

Another of Shephard’s charity challenges took place in early 2009 when he, along with eight other well-known celebrities, climbed Mount Kilimanjaro to raise money for Comic Relief. Joining him on the climb were Cheryl Cole, Kimberley Walsh, Fearne Cotton, Gary Barlow, Alesha Dixon, Ronan Keating, Denise van Outen and Chris Moyles. The team raised £3,326,000 in total.

On 30 June 2010, Shephard announced his departure from GMTV, two months before the end of the programme, stating that he wished to spend more time with his family and focus on his charity work. Ben presented his final episode of GMTV on 30 July 2010, before the programme was axed two months later in September. The show was later replaced by Daybreak hosted Adrian Chiles and Christine Bleakley and then later by Lorraine Kelly, Kate Garraway and Aled Jones.

On 27 July 2010, Shephard announced that he had signed a new contract with Sky Sports, where he presented Goals on Sunday alongside Chris Kamara in a deal reportedly worth £495,000 a year. He also hosted live secondary match coverage of the UEFA Champions League on Sky Sports 3 or 4, while the main coverage on Sky Sports 1 is hosted by Jeff Stelling. He was the main anchor for Sky Sports coverage of the League Cup. As of April 2014, Shephard only presents Goals on Sunday for Sky Sports and no longer hosts any of the live matches.

Shephard holds a Guinness World Record. In 2010, he set the record for smashing the most pumpkins in one minute. In 2008 he held the record for the Highest reverse bungee jump which was beaten in 2010 by David Hasselhoff; and he held the record for tossing the most pancakes in one minute in 2009, but was beaten the following day by Aldo Zilli.

In 2010, Shephard and his friend Ivan ran the Coast-to-Coast Challenge, raising over £120,000 for the Children’s Heart Unit Fund at the Freeman Hospital in Newcastle upon Tyne. The run was 145 miles long and took them five days.

In 2011, Shephard fronted an eight-part game show for Sky1 called Safebreakers.

Shephard also spent a long time and became good friends with 12-year-old Harry Moseley, who had supported Cancer Research UK for many years, despite suffering from brain cancer himself. Harry dedicated a lot of his time to help others who had cancer and, with the help of Shephard, has been able to help more people beat cancer. In September 2011, Harry Moseley died but Shephard remains involved with Harry’s family and is now an ambassador for the Help Harry Help Others campaign in his memory.

In March 2011, Shephard designed blue and black striped hipsters for charity to help raise awareness of Prostate Cancer.

In June 2012, Shephard made a guest appearance on the sports-based panel show A Question Of Sport. The following month he announced that he had permanently left the BBC in order to concentrate on his work with Sky Sports and ITV.

Shephard returned to Channel 4 in 2013 to co-present cookery programme called What’s Cooking?. He hosted one series, alongside Lisa Faulkner, and then permanently left Channel 4 on 24 May 2013.

Shephard co-presented two episodes of the factual series Mystery Map with Julia Bradbury, which aired for two episodes on 20 November 2013 and 27 November 2013 respectively.

In 2013, Shephard was the face of Warburtons lunch thins. He has been on the judging panel for Pride of Britain Awards numerous times.

After just four years on air, Daybreak was axed in spring 2014 to make way for a brand new ITV Breakfast programme Good Morning Britain. It was announced on 3 March 2014, that Shephard would be a presenter on the newly launched programme. Ben’s first show was on 28 April 2014 and he currently hosts the show on Thursdays and Fridays alongside Susanna Reid (Thursday) and Kate Garraway (Friday).

On 13 January 2014, Shephard joined his friend Ivan and burned ten thousand calories for the charity Seb4Chuf. However, despite this, Ben had warned his Twitter followers that if he picked up any injuries in the process, he might not be able to take part in 2014’s Soccer Aid. He was able to play in the 2014 England squad.

Shephard has presented the popular daytime game show Tipping Point since 2012, as well as celebrity episodes known as Tipping Point: Lucky Stars since 2013. In June 2015, it was announced that Tipping Point had been renewed for two further series to air in 2016 and 2017.

Since 2015, Ben has co-presented the Saturday night game show Ninja Warrior UK for ITV. He presents the show alongside Rochelle Humes and Chris Kamara. The first series began airing on 11 April 2015 and a second series began on 2 January 2016. A third series of Ninja Warrior UK began on 31 December 2016.

In 2017, Shephard was asked to do the Full Monty to raise awareness of Prostate Cancer, but he declined the offer due to other filming commitments.

In September 2017, he played as part of Les Ferdinand’s team for Game 4 Grenfell.