In March 2009, Frankel's book, Naturally Thin: Unleash Your SkinnyGirl and Free Yourself from a Lifetime of Dieting, was published and The SkinnyGirl Dish: Easy Recipes for Your Naturally Thin Life, was published in December. She created an exercise DVD, Body by Bethenny, in spring 2010 and an audiobook, The Skinnygirl Rules, which summarized her two prior books. In 2011, Frankel published, A Place of Yes: 10 Rules for Getting Everything You Want Out of Life and in December 2012, published the novel Skinnydipping.
Frankel created a pre-packaged margarita line, named Skinnygirl Margarita, in 2009, which led to Frankel founding the company Skinnygirl and the cocktail line, Skinnygirl Cocktails. The company has since created products such as "candy, deli meat, sweeteners, popcorn, salad dressings, shapewear, and most recently, jeans and apparel." She sold the cocktail line to Beam Global for $120 million in 2011.
Frankel posed nude for a PETA billboard in September 2009.
In November 2009, her father Robert J. Frankel passed away.