Bokoko started her career in 1997 as a legal assistant at Carbo & Martinez Law firm in Valencia, Spain. From 1999 to 2005 Bokoko was the Director of IVEX, the Valencia Institute of Export where she helped Spanish businesses ranging from food, lifestyle goods to beverages and spirits enter the US market. Bisila Bokoko operated as the Executive Director of the Spain-US Chamber of Commerce from 2005 to 2012.

Bokoko attended Universidad San Pablo Madrid, Spain where she earned an MBA in Business Administration and Economics in 1998. That same year, Bokoko earned a certificate of British Law at the University of Manchester and completed a MA in International Relations at the City College of New York in 2003.

In 2009, Bokoko founded BBALP (Bisila Bokoko African Literacy Project), a nonprofit organization headquartered in New York City. With current presence in Ghana, Kenya, Zimbabwe and Uganda. BBALP is committed to promoting literacy across the continent through the opening of libraries. The motto is : “with a book, you are never alone”.

In 2010, she launched Bisila Wines, an international wine brand made in Spain. In 2012, she opened BBES, a New York-based global business development agency. The firm consults businesses in the fields of fashion, lifestyle, arts and culture. In December 2019, Bokoko was featured in the Visual Collaborative Polaris catalog, under the Supernova series for humanities, she was interviewed alongside people such as; Nse Ikpe-Etim, William Coupon and Nere Teriba.

On 17 April 2013, Bokoko hosted the Pikolinos Maasai Gala at the United Nations in collaboration to support the Kenyan tribe. Through the Maasai Project, over 1,600 Maasai women hand embroider leather onto Pikolinos shoes and bags enabling them to earn a stable income while preserving their cultural heritage and way of life.

In October 2014, she co-hosted UNCTAD’s EMPRETEC Women in Business Awards (E-WBA) ceremony in Geneva, Switzerland during the World Investment Forum. Bokoko serves as a Spokesperson for Pikolinos, Agatha Ruiz de la Prada and The Liceu Barcelona Opera House US Foundation.