Brandon Morrow

On August 8, Morrow was one out away from a no-hitter against the Tampa Bay Rays when Evan Longoria hit an infield single. It would have been the first no-hitter by a Blue Jay since Dave Stieb's no-hitter on September 2, 1990. He finished the one-hitter for his first complete game while compiling 17 strikeouts, a career high for Morrow in a game and one strikeout shy of the team record 18 strikeouts set by Roger Clemens in 1998. According to the Game Score metric devised by sabremetrician Bill James, this tied for the fourth-highest rated pitching performance since 1920, with a game score of 100.

He was selected by the Anaheim Angels in the 40th round, 1200th overall, in the 2003 Major League Baseball Draft. However, he did not sign with the Angels and decided to attend college at UC Berkeley. He majored in American studies.

He was a Cape Cod League All-Star in the 2006 summer for the Yarmouth-Dennis Red Sox, striking out 24 batters in 15 innings with a 1.84 ERA and three saves. He was named a third-team preseason All-American and the fifth-best professional prospect out of the Cape Cod League by Baseball America.

In his first professional season in 2006 he split time between Arizona League Mariners appearing in seven games and Single-A Inland Empire 66ers appearing in one game of the California League. He posted an 0-2 record overall with a 2.25 ERA in 16 innings striking out 17 batters and starting five games. He pitched three hitless innings for Inland Empire during his brief time there.

Morrow was invited to spring training in 2007. He went 0-1 with a 1.08 ERA in 6 relief appearances and made the major league club despite being considered a long-shot to make the club at the start of spring.

After missing two weeks of spring training in 2008 due to a sore shoulder, Morrow was optioned to the Mariners minor league affiliate Double-A West Tennessee on March 30. Morrow was recalled to the Seattle bullpen 17 days afterwards when Mariners starter Érik Bédard was placed on the 15-day disabled list. When Seattle's regular closer J. J. Putz became injured on June 12, Morrow took over his duties. Including a closing appearance on June 11, Morrow saved 8 games in 8 tries, before a July 10 opportunity when he gave up two solo home runs to the Oakland Athletics to acquire his first blown save. He had only given up 2 runs all year prior to that, and had 40 strikeouts in 36.2 innings pitched, and a very low ERA of 1.76 and WHIP of 0.88.

On March 29, 2009 the Mariners announced that Morrow would no longer be used as a starting pitcher; instead, he would move into a relief role with the organization. Morrow, who has Type 1 diabetes, acknowledged that his diabetes was a factor in the decision, saying that it was easier to balance his blood sugar in a relief position.

On December 22, 2009, the Mariners traded Morrow to the Toronto Blue Jays for pitcher Brandon League and minor league outfielder Johermyn Chávez.

On August 29, the Blue Jays announced that after his next start, Morrow would be shut down for the season to protect his arm. He pitched more innings in 2010 (146⅓) than in any of his previous seasons. He finished the season with a 10–7 record, 4.49 ERA, and 178 strikeouts. Morrow was nominated as one of 2010's "Ten People Making a Difference in Diabetes".

Morrow throws a hard fastball which sits between 92 and 100 mph. He has the ability to throw several off-speed pitches, including a slider (85–89 mph), curveball (81–85 mph), and change-up (81–87 mph). In September 2011, Morrow debuted a new cut fastball which comes from making a slight adjustment on his slider, with velocity hovering around 88–91 mph.

On February 5, 2013, manager John Gibbons named Morrow the number 2 starter for the upcoming season, behind reigning NL Cy Young Award winner R.A. Dickey. After opening the season with a 2–3 record and a 5.63 earned run average, Morrow was placed on the 15-day disabled list on June 1 with a right forearm strain. He made his first rehab start at High-A Dunedin on June 17, and pitched just 2 innings. On June 18, it was announced that Morrow had been pulled from rehabilitation after suffering an unnamed setback during his start. An MRI that day revealed only inflammation, and no structural damage in Morrow's arm.

On July 24, it was reported by Rogers Sportsnet that Morrow was diagnosed with an entrapped radial nerve in his right forearm, and would likely miss the rest of the 2013 season. Blue Jays management said the following day that they expected Morrow to pitch again in 2013, either in late September or in October's instructional league in Florida. Manager John Gibbons later said on August 22 that Morrow would remain on the disabled list for the rest of the season. In 2013, Morrow posted a record of 2–3, a 5.63 earned run average, and 41 strikeouts over just 54⁄3 innings pitched.

Morrow struggled throughout early spring training, giving up 7 earned runs through just 8 innings pitched. On March 18, manager John Gibbons confirmed that Morrow would be the team's fifth starter, citing a need to give him more time to prepare for the regular season. After struggling to open the season, including a start on April 26 where he walked 8 Red Sox batters over 2⁄3 innings, Morrow was placed on the 15-day disabled list on May 3 with a sprained right index finger. Later that day his injury was determined to be a more severe torn tendon sheath in his right hand, and he was transferred to the 60-day DL. Morrow made his first rehab appearance on August 27 with the Dunedin Blue Jays, pitching one scoreless inning. He was activated from the 60-day DL and added to the Blue Jays active roster on September 1, 2014. On November 1, the Blue Jays declined Morrow's $10 million 2015 option, making him a free agent.

On December 16, 2014, Morrow signed a 1-year, $2.5 million contract with the San Diego Padres. He made 5 starts with the Padres in 2015, posting a 2.73 ERA and 23 strikeouts, before going on the disabled list with right shoulder inflammation in early May. He remained on the disabled list into August, when it was determined that he required season-ending surgery to correct a shoulder impingement. On December 17, Morrow signed a minor league contract with the Padres that included an invitation to spring training.

On January 25, 2017, Morrow signed a minor-league contract with the Los Angeles Dodgers that included an invitation to major league spring training. He did not make the major league team and was assigned to the Triple-A Oklahoma City Dodgers to begin the season. Morrow was called up by the Dodgers on May 29, due to a clause in his contract that would have forced the Dodgers to waive him if he wasn't called up. By the end of the season, Morrow had settled into a role as the Dodgers' setup man. In 45 appearances out of the Dodgers bullpen, he was 6–0 with a 2.06 ERA with 50 strikeouts and two saves.

Morrow allowed one run in 3⁄3 innings in the 2017 NLDS, zero runs in 4⁄3 innings in the 2017 NLCS and five runs in 5⁄3 innings in the 2017 World Series. He was only the second person in history to pitch in all seven games of the World Series.

On December 12, 2017, Morrow signed a two-year, $21-million contract with the Chicago Cubs.

On June 20, 2018, Morrow was placed on the 10-day disabled list due to back tightness.

On August 21, 2019, he was shut down for the season due to lingering problems in his elbow. On November 4, 2019, Morrow elected free agency. On December 14, 2019, Morrow resigned with the Cubs on a minor league deal.

The Cubs organization released Morrow on July 8, 2020.