Her father, Don Epperson, was both a country singer and a co-star of Big Jake with John Wayne. After his sudden death in 1973, Brenda’s mother was left to raise two daughters.

When Eileen Davidson decided to quit The Young and the Restless in 1988, Epperson was chosen to replace Davidson because they looked so similar to one another. At the time, Epperson was working as a waitress with a caterer.

Epperson is a host on the UStream series, Actors-E Chat, where she interviews other celebrities. In October 2013, she began coordinating the Ascend Conference for women. She married the producer and writer, Lorenzo Doumani, in 1994.

In March 2013, she released a 3-song EP titled, “Take Time,” on her own label, which is available worldwide on iTunes, Amazon, Google Play, and CDBaby. That same year, Epperson joined the Board of Directors at Idle Tuesdays Recording Studio, a non-profit record label founded by Emily Hibard and based in Los Angeles.