Watson was born and raised in Bagdad, Florida, near Pensacola. He played on the golf team at Milton High School, which had featured future PGA Tour members Heath Slocum and Boo Weekley just before he attended. Watson played golf for Faulkner State Community College in nearby Baldwin County, Alabama, where he was a junior college All-American. He transferred to the University of Georgia, the defending NCAA champions, and played for the Bulldogs in 2000 and 2001. As a junior, Watson helped lead the Bulldogs to the SEC title in 2000.

Watson turned professional in 2002 and joined the Nationwide Tour where he played until 2005. He finished 21st on the Nationwide Tour’s money list in 2005, making him the last player to qualify for the following year’s PGA Tour. As a rookie in 2006, he earned $1,019,264 (90th overall) and led the PGA Tour in driving distance at 319.6 yards (292.2 m). His longest drive in professional competition was 424 yards (388 m) on the PGA Tour at the WGC-Bridgestone Invitational.

Watson was nicknamed by his father after the former professional American football player Bubba Smith. Watson is married to Angela “Angie” Watson (née Ball), a 6 ft 3 in (1.91 m) Canadian whom he met at Georgia while he was on the golf team and she was on the women’s basketball team. They were married in September 2004. In 2009, she was diagnosed with an enlarged pituitary gland, which accounts for her height.

*Note: The 2008 CVS Caremark Charity Classic was stopped after 28 holes due to heavy rain.

Watson claimed his first PGA Tour win on June 27, 2010, in Cromwell, Connecticut, at the Travelers Championship on the second hole of a sudden-death playoff with Corey Pavin and Scott Verplank. Watson tearfully dedicated the win to his parents, specifically his father who was battling cancer.

Unable to have a child naturally, various family issues, including the illness and death of Watson’s father in 2010, kept them from attempting to adopt until 2011–12. In March 2012, one week after a potential adoption fell through at the last moment, Watson and his wife adopted a one-month-old baby boy named Caleb. In late 2014 the Watsons adopted a baby girl.

Watson’s father, Gerry Sr., died on October 15, 2010 of throat cancer. His mother is Molly Marie Watson and he has a sister, Melinda Watson Conner.

On January 30, 2011, Watson won his second PGA Tour event, the Farmers Insurance Open, finishing one stroke ahead of runner-up Phil Mickelson. Watson picked up his second win of the 2011 season and third career PGA Tour title on May 1 when he defeated Webb Simpson at the second playoff hole at the Zurich Classic of New Orleans. Both players birdied the first playoff hole, with Watson holing a 12-footer; he birdied the next hole to win the tournament.

In July 2011, Watson provoked controversy by criticizing the Alstom Open de France on the European Tour, in which he was playing under a sponsor’s exemption. He indicated after his first round that he would not be playing any further events on the European Tour, and complained after his second round about security and organization at the tournament.

In 2011, he made a humorous appearance in the song “Michael Jackson” by Christian hip hop artist Andy Mineo on the album Formerly Known. He was featured in the song “Ima Just Do It” by KB, another Christian hip hop artist, on the album Tomorrow We Live. His prototype Golf Cart Hovercraft, the BW1, YouTube video has earned more than 8 million views.

Watson purchased a General Lee car from the television series The Dukes of Hazzard at auction for $110,000 in 2012. Following the Charleston church shooting in June 2015, display of the Confederate flag – which is featured on the car’s roof – became the subject of renewed controversy. Watson responded by saying he would paint over the flag with the American flag.

Watson purchased the mansion in the Isleworth community of Windermere, Florida, that was previously owned by Tiger Woods. In 2013, he was added to the list of Great Floridians by Governor Rick Scott.

Watson won the Travelers Championship to move him to third in the Official World Golf Ranking. He garnered his second victory in 2015 by winning the unofficial Hero World Challenge in the Bahamas, besting fellow American Patrick Reed by three strokes.

In 2015, Watson moved to Pensacola, where he has become very involved in the community. Among other ventures, Watson opened an ice cream store, purchased a part ownership in the Pensacola Blue Wahoos Minor League Baseball team, and purchased a Chevrolet dealership in nearby Milton, Florida. Watson has made considerable donations to Studer Family Children’s Hospital in Pensacola. He recently announced that he plans to run for mayor of Pensacola at some future date.

The 2018 season started with a T7 at the QBE Shootout in December 2017 marking the best of his first six starts. Watson returned to the winner’s circle with a 12-under finish at the Genesis Open in February, his third victory at this tournament (2014, 2016), all at Riviera. His trifecta at the Genesis (previously known as the Los Angeles Open, Northern Trust Open, and Nissan Open) makes him only the fifth to win this long-standing event at least three times, along with Ben Hogan, Arnold Palmer, Lloyd Mangrum, and Macdonald Smith. On March 25, he gained his eleventh tour win at the WGC-Dell Match Play event in Austin, Texas, with a winner’s share of $1.7 million. On June 24, 2018, he won again at the Travelers Championship winning $1.26 million at TPC River Highlands. This was his third career victory at the Travelers tournament (2010, 2015).

In September 2018, Watson qualified for the U.S. team participating in the 2018 Ryder Cup. Europe defeated the U.S. team 17 1/2 to 10 1/2. Watson went 1–2–0. He lost his singles match against Henrik Stenson.