Aguilar first appeared on radio in 1990. Her debut single “Ninja”, taken from the album of the same name, became a hit among Thai listeners. It was followed by the release of some other pop dance singles, including “Plik Lock (พลิกล็อค)” and “Prawatsart (ประวัติศาสตร์)”, and some ballads, like “Hua Jai Kor Ma (หัวใจขอมา)” and “Plao Rok Na (เปล่าหรอกนะ)”. Aguilar broke records by being the first female artist with a million-seller album in Thailand.

Arwut Lab (Secret Weapons) was released in 1992. The video of the album’s lead single, “Jing Mai Klua (จริงไม่กลัว)”, won MTV Asian Viewers Choice Award in Los Angeles, USA. It was the second music video by a Thai artist to win this award after Thongchai McIntyre. In the album’s second video, “Wela Mai Chuai Arai (เวลาไม่ช่วยอะไร)”, Aguilar costarred with a Chinese-American actor Michael Wong. The album has sold over a million copies, like its predecessor.

In 1994, Aguilar released her third album “Red Beat”. With a faster beat and a modern and sexy appearance, it became her most successful album to date, containing two of her most successful singles. One is the dance single “Mai Yag Rok (ไม่อยากหรอก)” and the other is the love ballad “Rak Thur Thee Sood (รักเธอที่สุด)”. This was the third time that an Aguilar album sold more than one million copies. The album eventually reached the mark of three million copies sold, being the only female album to do so in Thailand. This album also became the third biggest-selling album of all time in Thai music history, only behind two albums of Thongchai McIntyre.

In 1999, Aguilar explored a younger and more colorful image with her fifth album 5th Avenue. It spawned the hit single “Oon Jai (อุ่นใจ)”. It has been sold almost a million copies.

Her sixth album Dancing Queen was released in 2001. It was met with moderate reception. It was the first time Aguilar released a slow ballad as a lead single instead of uptempo one. However, “Kid Pid Kid Mai (คิดผิด คิดใหม่)”, has managed to top several radio charts. Due to heavy piracy situation during that time, the album became her smallest-selling album since her debut, selling approximately 670,000 copies.

In 2003, Aguilar released her seventh album, Paradise. The album contained Latin sound. It spawned three singles: “Sawan Yoo Thee Jai (สวรรค์อยู่ที่ใจ)”, “Hong Derm (ห้องเดิม)”, and “Yak Fung Kum Nun Talod Pai (อยากฟังคำนั้นตลอดไป)”. Paradise received well receptions, being sold over 760,000 copies. Four years later, Aguilar released her eighth album C.Space, featuring singles “Koh Khoom Laew”, “An Everlasting Love”, and “Wang Meed Dai Rue Yung”. This was during an important change in Thai music industry when no cassette was released anymore.

Aguilar has not released any studio albums since C.Space. She has mainly focused on live performances and concerts. In late 2008, she started working on a project, Mai – Tina: Beauty on the Beat, collaborating with Mai Charoenpura. The new single “Burn” was produced and the concert was due on June 6, 2009. In 2010, Aguilar performed with various artists, including Tata Young, Mai Charoenpura, Marsha, Jetrin Wattanasin, and Dan, on a special project called “This is It, the Concert”, a tribute to Michael Jackson, after his death in 2009. It took place on February 21 and 22, 2010 at the Impact Arena in Bangkok.

Aguilar celebrated her 20th career anniversary on December 21, 2010. She held celebratory concerts on June 4 and 5, 2011 at the Royal Paragon Halls.

In 2016, at the “Million Albums Concert” (คอนเสิร์ตล้านตลับ), Aguilar performed with various artists including Tata Young, Mai Charoenpura, Myria Benedetti, Beau Sunita, and Nicole Theriault on October 7–9, 2016 at Royal Paragon Hall.