Meltzer’s television career began in 1997 when she hosted Lattjo Lajban with David Hellenius. In 2001 Meltzer hosted the dating show När och fjärran and the following year she presented the Swedish version of Popstars for Kanal 5. In 2004 Dagens Nyheter called Meltzer “something rare in Swedish scenes: a young girl that both can and dare let stylish clip blanket and be asrolig”.

In 2005 Meltzer’s big break came when she was one of three comedians to star in the comedy show Hey Baberiba. She did impressions for many well known celebrities including Carola Häggkvist, Lena Philipsson, Pernilla Wahlgren, Queen Silvia and Tina Nordström. In 2007 she took part in the first series of Tack gode gud (Swedish version of the Australian Thank God You’re Here).

In 2010 Meltzer, together with Måns Zelmerlöw and Dolph Lundgren hosted the 2010 edition of the Melodifestivalen., the winner of the festival was Anna Bergendahl with the song This Is My Life, in addition Meltzer provided the SVT television commentary at the 2010 Eurovision Song Contest along with Edward af Sillén. In 2011 she hosted the 2011 edition of Inför Eurovision Song Contest.