Born in Murcia, Aquino made his professional debuts for local Real Murcia at only 16 years of age, during 2006–07 in the second division, against CD Tenerife: he scored in a 1–4 home loss for his only appearance of the season, which ended in promotion. In early 2007, rumours surfaced that Chelsea and Liverpool, amongst others, were after the youngster; eventually no deals were arranged, as the player chose to stay in the country to further his development.