In 2006, through 12 games, Woodhead rushed for 2,740 yards, a new all-division single season rushing record, surpassing Kavin Gaillaird. Including the playoffs, his rushing yards in 2006 totaled 2,756. He also led his team to the NCAA Division II playoffs in 2006, losing to Northwest Missouri State. Northwest Missouri State managed to hold Woodhead to a season low 16 yards rushing on 16 carries while giving up 79 yards receiving, which was more than double anyone on the Northwest Missouri team. Chadron also had 327 yards of total offense compared to Northwest Missouri State's 306.
Barry Sanders is the only college player to accumulate more all-purpose yards than the 3,159 that Woodhead gained in 2006, as he gained 3,250 as a junior at Oklahoma State University in 1988, when he won the Heisman Trophy. Woodhead ranked 10th in Division-II in career all-purpose yards with 7,349 after his junior season. The Division-II leader is Brian Shay of Emporia State with 9,301 yards, including 1,207 on kickoff returns, 1995–1998.