Howe was not the first to conceive of the idea of a sewing machine. Many other people had formulated the idea of such a machine before him, one as early as 1790, and some had even patented their designs and produced working machines, in one case at least 80 of them. However, Howe originated significant refinements to the design concepts of his predecessors, and on September 10, 1846, he was awarded the first United States patent (U.S. Patent 4,750 ) for a sewing machine using a lockstitch design. His machine contained the three essential features common to most modern machines: a needle with the eye at the point, a shuttle operating beneath the cloth to form the lock stitch, and an automatic feed.
Despite securing his patent, Howe had considerable difficulty finding investors in the United States to finance production of his invention, so his elder brother Amasa Bemis Howe traveled to England in October 1846 to seek financing. Amasa was able to sell his first machine for £250 to William Thomas of Cheapside, London, who owned a factory for the manufacture of corsets, umbrellas and valises. Elias and his family joined Amasa in London in 1848, but after business disputes with Thomas and failing health of his wife, Howe returned nearly penniless to the United States. His wife Elizabeth, who preceded Elias back to the United States, died in Cambridge, Massachusetts shortly after his return in 1849.