In 1959, Pucci decided to create a lingerie line. His atelier in Rome advised him to develop the line abroad, avoiding the difficulties of a decade earlier in matching available fabrics to the patterns of his first swimwear line. As a result, Pucci came to Chicago giving the lingerie contract to Formfit-Rogers mills. The venture proved to be successful, and Pucci was made vice president in charge of design and merchandising for the company a year later.
In February 1959, he married Cristina Nannini from Rome about whom he later remarked, "I married a Botticelli". They had two children, Alessandro and Laudomia. Alessandro died in a car crash in 1998, six years after his father.