On September 28, 2011, Longoria hit a walk-off home run in extra innings against the New York Yankees to give the Rays an 8-7 victory, and more importantly, a spot in the playoffs. Earlier in the month, the Rays were facing a deficit of nine games in the wild card race to the Boston Red Sox. However, an epic collapse of the Red Sox, where they went 7-20 in the final games of the year, and a surge of the Rays, allowed them to overtake the Red Sox and eliminate them on the final day of the regular season. Longoria's home run came just three minutes after the Red Sox suffered a walk-off loss to the Baltimore Orioles.
Some of his 2013 highlights included playing in the most games of his career with 160; he missed two with a foot injury. He had a walk-off home run vs. the San Diego Padres on May 11 when the Rays were down, 6–7. It was his first walk-off home run since the Game 162 walk-off against the New York Yankees in 2011.
On March 8, 2011, his classic 1967 black and white Camaro RS, valued at $75,000, and a Buick GSX, valued at $25,000, were reported stolen from an Arizona lot. Longoria lives in California, but was having work done on the cars in Arizona.
On March 28, 2011, Longoria, David Price and Reid Brignac's rental property in Port Charlotte, Florida, was broken into, while they were away at the nearby Charlotte Sports Park stadium for a game. According to the St. Petersburg Times, police estimated $56,000 in lost property from the burglary. Among the loot was Longoria's AK-47 rifle.
A video showing Longoria being interviewed during batting practice when a foul ball flies in the direction of the reporter and is intercepted bare handed by the baseball player was published on YouTube on 6th May 2011. As of 16th May, the video already had 1.2 million views. As of July 2020, the video had more than 10 million views.