Farruko began his career in 2009. He credits Myspace with helping him create a fan base that would eventually result in him becoming a popular singer. In 2011, Farruko appears on a song with José Feliciano called Su hija me gusta, where a young man tells a father I like your daughter. As his style developed he typically directed his music to younger people and relationships. As his songs grew in popularity online, Puerto Rican radio stations picked up on the internet hype and began to broadcast Farruko to a wider audience, solidifying his presence in the Reggaeton scene.

Farruko was nominated for the Latin Grammy Award for Best Urban Music Album in 2012. In the Summer of 2014, Farruko’s his songs, “Passion Whine” and “6 AM”, both with J Balvin, reached spots 1 and 2, respectively.”Passion Whine” ranked on the Top Latin Songs list, published by Monitor Latino, for 26 consecutive weeks. The song “6 AM” earned Farruko nominations at Premios Juventud for Best Urban Fusion/Performance for “6 AM” and Best Urban Song at the 15th Annual Latin Grammy Awards.

On April 3, 2018, Farruko was arrested in Puerto Rico, accused of hiding $52,000 in undeclared cash in shoes and luggage when returning from the Dominican Republic for which he was required to do three years of probation. As of 2017, he had a net worth of $3 million.