Andrade became interested in acting and film during high school. She was cast in her first professional role when she was 15 years old, when she appeared in the 2000 HBO biopic, For Love or Country: The Arturo Sandoval Story, which starred Andy García as the Cuban jazz musician, Arturo Sandoval. Andrade played Paloma, Sandoval’s daughter-in-law, in the television film.

Andrade moved from Florida to Los Angeles when her agent relocated to Southern California. She appeared in several short films and television series during the 2000s and 2010s, including guest spots on CSI: NY and Law & Order: Los Angeles. In 2006, she starred in the ABC Family miniseries, Fallen.

In 2011, she was cast in a recurring role in season four of Sons of Anarchy.

She remained a relatively unknown actress until the debut of her 2012 horror film, The Devil Inside. The film, which stars Andrade, Simon Quarterman, Evan Helmuth, and Suzan Crowley, was produced on a shoe-string budget, but debuted in January 2012 with $34.5 million to win its opening weekend.

In 2016, she was cast as Christina Santos in the pilot episode of the Marvel’s Most Wanted, but the series was not picked up by ABC.

Andrade married musician Josh James in August 2017 in a ceremony in Pala, California.