A life-member of the Actors Studio, having studied there under Lee Strasberg, De Sapio began teaching there as well In the early 1980s. In 1985 she co-founded with Giuseppe Perruccio the Duse Studio in New York City, an international centre for training in acting, film production and theater. In 1987, Duse moved to Montecatini Terme, Italy, and then to its current base in Rome.
