Lindor was born in Caguas, Puerto Rico, on November 14, 1993, the third of four children of Miguel Angel Lindor and Maria Serrano. He began playing baseball at a young age, assisted by his father, who would hit him ground balls from the top of a hill while the younger Lindor stood partway down the slope, attempting to field them. Lindor moved to Central Florida at the age of 12, with his father, stepmother and youngest sibling, and was enrolled at the Montverde Academy prep school. After he signed with the Cleveland Indians in August 2011, his mother and two older siblings joined him in Florida.

In 2010, he played for the 18U United States team in the 2010 World Junior Baseball Championship, in Thunder Bay, Ontario. They finished in fifth place despite only losing one game. Lindor was named to the All-IBAF Juniors Team in his position at short-stop.

Lindor began his professional career with the Short-Season A New York-Penn League Mahoning Valley Scrappers during the 2011 season and appeared in five games. MLB.com rated Lindor as the 32nd best prospect in baseball before the 2012 season. He was assigned to the Lake County Captains of the Class A Midwest League, and named to appear in the 2012 All-Star Futures Game. In 122 games for Lake County, Lindor had a .257 batting average with six home runs, 42 RBIs, 33 extra-base hits and 27 stolen bases.

Lindor attended Montverde Academy in Montverde, Florida. The school’s baseball facility was named after him in 2013. He was named to the USA Today All-USA high school baseball team. The Indians drafted Lindor in the first round (eighth overall) of the 2011 MLB draft. He had full-ride scholarship offer in place with the Florida State Seminoles baseball team, but chose to sign with the Indians for $2.9 million in August. In September, Lindor was drafted by the Indios de Mayagüez in the second round of the Liga de Béisbol Profesional Roberto Clemente’s (LBPRC) first year draft. However, he has been unable to play there due to Cleveland’s intervention. On May 7, 2014, the Indios de Mayagüez traded Lindor’s LBPRC player rights to the Gigantes de Carolina in exchange for Carlos Correa. However, only two weeks later the Cangrejeros de Santurce signed him by exploiting a legal loophole declaring that any player that has not been officially contracted within three years after being drafted is considered a free agent.

Prior to the 2013 season, Baseball America ranked him as the Indians top prospect. Lindor started the 2013 season with the Carolina Mudcats of the Class A-Advanced Carolina League. He was promoted to the Akron Aeros of the Class AA Eastern League on July 15, 2013. Between the two levels, Lindor batted .303 with two home runs, 34 RBIs, 31 extra-base hits, and 25 stolen bases in 104 games.

Lindor began the 2014 season with Akron. The Indians promoted Lindor to the Columbus Clippers of the Class AAA International League on July 21, 2014. In 126 games between the two clubs, he batted .276 with 11 home runs, 62 RBIs, and 28 stolen bases. Lindor began the 2015 season with Columbus.

The Indians purchased Lindor’s contract from Columbus on June 14, 2015 and added him to the active roster. In 59 games for Columbus prior to his promotion, he was batting .284 with two home runs and 22 RBIs. He made his debut with the Indians that day as a pinch hitter. He stayed in the game and recorded his first major league hit. Lindor won the American League (AL) Rookie of the Month Award for September, during which he batted .362. He finished the 2015 season with a .313 batting average, 12 home runs, 51 RBIs, 12 stolen bases and 22 doubles in 99 games for the Indians. He placed second in the AL Rookie of the Year Award voting.

In 2016, Lindor finished season with a .301 batting average, 15 home runs, 78 RBIs, 19 stolen bases, 15 sacrifice flies (leading the majors), and 30 doubles in 158 games for the Indians. He was named a Gold Glove Award Finalist in the AL Shortstop position along José Iglesias and Andrelton Simmons. In the 2016 MLB postseason, Lindor’s seven multi-hit games broke the record for most ever for a player less than 23 years old. His 16 postseason hits are also the most hits by a Cleveland batter since 1997, and he’s the youngest Cleveland batter to have six World Series hits. Following the 2016 season, Lindor was presented with his first Gold Glove Award and first Platinum Glove Award. Lindor was the 2016 Esurance MLB/This Year in Baseball Award winner for Best Defensive Player. He finished ninth in the AL Most Valuable Player Award (MVP) voting.

On April 5, 2017, Lindor hit his first career grand slam, doing so against the Texas Rangers, as the Indians won 9−6 and swept the season-opening series. On July 22, 2017 Lindor hit his first career walk-off home run in the 10th inning versus the Toronto Blue Jays for a 2−1 victory.

In 159 games for Cleveland, Lindor batted .273 with 33 home runs and 89 RBIs. End of season awards for Lindor in 2017 included selection as shortstop on Baseball America’s All-MLB Team, and his first career Silver Slugger Award at shortstop. He finished fifth in the AL MVP voting, and was selected as the cover athlete of the video game R.B.I. Baseball 18.