Gedeon Burkhard was born in Munich, West Germany, the son of Wolfgang Burkhard and German actress Elisabeth von Molo (then Burkhard) who is granddaughter of Alessandro Moissi, a famous Albanian actor of the 20th century. Gedeon was educated at a boarding school in England and began his acting career in 1979 in the German TV film Tante Maria. His father, Wolfgang Burkhard, is his manager.

During the 1990s, he lived in the U.S.A, working in several productions, but without much recognition. Burkhard married Birgit Cunningham only to divorce three months later. After that, he lived in Vienna for Kommisar Rex for more than five years, before moving to Berlin for work reasons. Burkhard was working in Cologne on the TV series Alarm für Cobra 11 as the detective Chris Ritter, until the end of his contract in November 2007. His character Chris Ritter had a heroic death. He then returned to Berlin, to be close to his daughter and to work in new projects. He said: “For the moment I will dedicate myself again fully to my artistic vagabond life in Berlin”. Burkhard appeared in the Quentin Tarantino movie Inglourious Basterds. In February 2009, he was shooting the film Massel, made for German television. In 2011, he was in Rome, shooting an Italian mini TV series of 6 chapters Caccia al Re – La narcotici, in which he plays a drug investigator, Daniele Piazza.

In 2011, he competed in Ballando con le Stelle, the Italian version of “Dancing with the Stars”, accompanied by professional Italian dancer Samanta Togni, in which he danced with his “daughter” Laura Glavan.

In 2016, Burkhard played Gustav Froehlich, a German actor and UFA star, in the international movie “The Devil’s Mistress” (original title: “Lída Baarová”) by Czech director Filip Renč. The biographical film is about the life of actress Lída Baarová and her relationship with Joseph Goebbels. The film was theatrically released in January 2016 in Prague.