Tartakovsky was born Gennady Tartakovsky (Russian: Геннадий Тартаковский) on 17 January 1970, in Moscow, to Jewish parents. His father worked as a dentist for government officials and the Soviet Union national ice hockey team. Genndy felt that his father was a very strict and old-fashioned man, but they had a close relationship. His mother, Miriam, was an assistant principal at a school. He has a brother, Alexander, who is two years older and a computer consultant in Chicago. Before coming to the United States, his family moved to Italy. There, Tartakovsky was first drawn to art, inspired by a neighbor's daughter. Tartakovsky later commented, "I remember, I was horrible at it. For the life of me, I couldn't draw a circle".