His Broadway theater career began in 1957 and included turns as “M. Lindsey Woolsey” opposite Angela Lansbury in the original production of Mame; as “Owen O’Malley” in On The Twentieth Century, and creating the role of David in the original Broadway production of Company.

In 1979 he appeared as the head of Dustin Hoffman’s character’s advertising firm in the Academy Award-winning Kramer vs. Kramer. Coe was nominated for an Academy Award for the 1968 short film The Dove, a parody of Ingmar Bergman’s films, which he also co-directed. Coe also played the role of Brigadier General Scott Watson in the 1986 movie Remo Williams: The Adventure Begins. He guest-starred on a 1991 episode of Star Trek: The Next Generation. He also portrayed Ben Cheviot, the eventual head of Network 23, on the series Max Headroom. His various television appearances include Murder, She Wrote, Bones, My Wicked, Wicked Ways: The Legend of Errol Flynn, Judging Amy, The King of Queens, Nip/Tuck, Grey’s Anatomy, Columbo, Curb Your Enthusiasm, Gilmore Girls, The Golden Girls, Wilfred, and as Senator Howard Stackhouse in two episodes of The West Wing.

Coe died on July 18, 2015, at the age of 86, after a long illness, in Santa Monica, California. The eighth season of Archer (the primary arc of which revolves mostly around the death of his character Woodhouse) was dedicated to him.