On September 15, 2019, in Week 2 against the Arizona Cardinals, Hurst caught a one-yard touchdown pass from Lamar Jackson, the second of his career, as the Ravens won 23-17. In Week 14 against the Buffalo Bills, Hurst caught three passes for 73 yards, including a career-long 61-yard touchdown pass from Jackson that helped the Ravens eventually win 24–17 and clinch a playoff berth. Overall, Hurst finished the 2019 season with 30 receptions for 349 receiving yards and two receiving touchdowns.