In July 2001, Arakawa published the first chapter of Fullmetal Alchemist in Monthly Shōnen Gangan. The series spanned 108 chapters, with the last one published in July 2010, and the series was collected in twenty-seven volumes. Some reviewers say that the combination of Arakawa's art style and the writing in Fullmetal Alchemist contribute to its dark thematic elements. When the studio Bones adapted it into an anime series, Arakawa assisted them in its early development. However, she was not involved in the making of the script, so the anime had a different ending from the manga, which she developed further. The series won the 49th Shogakukan Manga Award in the shōnen category in 2004. When the second anime adaptation was reaching its ending, Arakawa showed director Yasuhiro Irie her plans for the manga's ending, making both end in near dates. Most reviewers distinguish between the manga and anime, which they attribute to differences in style and subject matter. One review explains that the manga is more "emotional," whereas anime is more whimsical. Arakawa's simple, dark style and plot choices contrast with the anime's "cartoony," colorful rendering. Reviews in general tend to ascribe the anime to children and the manga to teens and adults.