Patric began dating actress Julia Roberts days after she canceled her wedding to Kiefer Sutherland in June 1991.

In 1993, he starred alongside Gene Hackman and Robert Duvall as 1st Lt. Charles B. Gatewood in the movie Geronimo: An American Legend. His scenes in The Thin Red Line were cut before the film’s release. He appeared in the Alec Baldwin film The Devil and Daniel Webster, which was shot in 2001, and released in late 2007 as Shortcut to Happiness, but turned down the lead role in The Firm (1993), which went to Tom Cruise. He garnered excellent reviews for his performances as undercover narcotics officers in Rush (1991) and Narc (2002).

In 2005, Patric appeared on Broadway as “Brick” in a revival of Tennessee Williams’ Cat on a Hot Tin Roof, opposite Ashley Judd, Ned Beatty and famed character actress Margo Martindale. He next appeared on Broadway opposite Brian Cox, Chris Noth, Kiefer Sutherland and Jim Gaffigan in a revival of his father Jason Miller’s play, That Championship Season, which began previews on February 9, 2011 and closed on May 29, 2011. The play (written by Jason Miller) debuted in 1972, and won, among other awards, the Pulitzer Prize and the Tony Award.

In 2012, he began filming the Civil War film, Copperhead, but several weeks into the shoot, he was removed from the project by the director, Ronald F. Maxwell for “failing to take direction”. His replacement was Billy Campbell.

Patric dated Danielle Schreiber off-and-on for approximately 10 years. During the relationship they conceived a son through in vitro fertilization. Patric and Schreiber separated in May 2012. Schreiber’s attorneys argued that, under California law, Patric was a sperm donor as Schreiber and Patric had not married and the conception of the child was by artificial means, and therefore Patric has no custody rights to the son. Patric has been pursuing changes to the law that bars his parental rights. Patric then sued for parental rights over the child, but lost the case at the trial court level.

The Court of Appeal of California, however, also ruled that the California Family Code did not preclude him from establishing that he was presumed a parent based on his post birth conduct. The case was sent back down to the trial court level, and in late 2014 he was recognized legally as the father of his son with the court granting him parental rights. Following his initial loss in trial court, he lobbied the California legislature to give parental rights to sperm donors.