He was a captain of the North Miami Senior High School tennis team, editor of the school paper, and a teenage freelance reporter ("stringer") for The Miami Herald. Zucker also was president of his sophomore, junior, and senior classes, running on the slogan "The little man with the big ideas." He graduated from North Miami Senior High School in 1982. Before college, he took part in Northwestern University's National High School Institute program for journalism. Zucker went on to Harvard University. He was president of the school newspaper, The Harvard Crimson, during his senior year. As such, he encouraged the Crimson's decades-old prank rivalry with the Harvard Lampoon, then headed by future NBC employee Conan O'Brien, which culminated in Zucker having O’Brien arrested. Zucker graduated from Harvard in 1986 with a Bachelor of Arts in American history.