Jarre posted his first Vine in January 2013 on the day Vine launched. Three months after the launch of Vine, he released a video titled Don’t be afraid of love, which became one of the earliest viral videos on Vine and was featured twice on The Ellen DeGeneres Show. Six months after starting his Vine account, he had 20,000 followers. Most of his vines feature him playing pranks on strangers. According to Jarre, after being featured on The Ellen DeGeneres Show, his account grew from 20,000 followers to 1 million followers in a month. Subsequently, Ellen asked him to cover the Red Carpet ceremony of the 86th Academy Awards, where he made multiple vines with Hollywood actors. Later he was hired by Canal+ to cover 2014 Cannes Film Festival. At the Tribeca Film Festival 2014, he was one of the jurors of the 6 second films competition.

In November 2013, Jarre started a project on Vine called Humans. In this project, he asks strangers the question “what is the most important message you would like to share with the world right now?”. The videos of this project have been posted under a separate Vine account, Humans. BuzzFeed’s Arielle Calderon wrote of Jarre’s series that “this Vine project will restore your faith in humanity.”

GrapeStory is a talent agency founded by Jarre and Gary Vaynerchuk in May 2013. The agency connects mobile content artists with brands looking for marketing content. After gaining a significant following on Vine, Jarre decided to launch a talent agency for Vine, Instagram and Snapchat stars. Jarre was looking for a business partner when he learnt that Vaynerchuk was going to be in Toronto. Jarre had taught himself English by listening to an audio version of Vaynerchuk’s self-help book, Crush It! when he was in China. When Jarre pitched his idea, Vaynerchuk liked it and decided to become his business partner. Jarre then left his business in Toronto and moved to New York to work on GrapeStory. As of August 2013, the agency had between 20 and 30 Vine stars signed on, among others.

After gaining 7 million followers on Vine, Jarre made an account on Snapchat and started using the platform where he makes two-minute narratives for telling stories. Jarre created a snapchat story with Stromae about a carrot looking for his father (Stromae) On 11 July 2014, Jarre went outside Snapchat’s office and tweeted “Hey Snapchat, I am outside your office. Let me in if you see this.” The hashtag #JeromeInsideSnapchat that he used for his tweet trended at #1 in the US and the UK. He was then asked to come into the Snapchat office, where he made a Snapchat story with the CEO Evan Spiegel.

Jarre was strongly criticized by the Vine community for posting a Vine in which he played a kiss prank on John Stamos and Stamos returned the kiss. The vine was posted in June 2014, and the commenters accused him of being gay and threatened to unfollow him for it. Jarre posted a follow-up Vine video the next day to call out these individuals directly. In it, he claimed he’s not gay, then proceeded to kiss a fellow Vine star Nicholas Megalis on the mouth to show support for the LGBT community.

On January 5, 2014, Nash Grier and Jarre turned up at a mall in Kópavogur, Iceland to meet their fans. The meet up was organized by the two of them on the social media a day before. They wanted to do a free meet-up, so decided against booking a venue and hiring security. Over 5,000 people gathered there and the police had to be called after the crowd became unmanageable. Minor injuries and damages to the parked cars were also reported. Later Jarre posted an apology on Twitter.

In 2015 Jarre started the #UglySelfieChallenge, inviting people to stop trying to take perfect selfies, and post selfies making silly faces; everyone had to nominate three more people to do the same. More than 100,000 ugly faces photos were published.