Born in Philadelphia, Aglialoro grew up in Collingswood, New Jersey. He graduated from Collingswood High School in 1961 and Temple University in 1965.

Aglialoro served as CEO of Cybex International, a fitness equipment manufacturer, from 1997 until 2016 when it was sold to Brunswick Corporation. He is also chairman and CEO of UM Holdings Ltd., which he co-founded in 1973. As of 2019 Aglialoro is a borough commissioner for Tavistock, New Jersey, a borough with a population of 5 in 2010. He had previously served as the borough’s mayor.

Aglialoro is also a poker enthusiast, winning the US Poker Championship in 2004.

After almost two decades after acquiring the movie rights from the Estate of Ayn Rand, and having several notable producers option the rights, Aglialoro took it upon himself to see that Atlas Shrugged would finally go into production and independently financed its production and distribution through Atlas Productions, LLC. Since the novel is more than 1200 pages and separated into 3 parts, Aglialoro determined that filming each part separately would allow him to cinematically deliver more of its powerful message. Aglialoro produced Atlas Shrugged Part 1 with Harmon Kaslow and shared screenplay credit, too. On April 15, 2011, the film version of Atlas Shrugged: Part I, premiered in 299 selected cities throughout the United States and ultimately played on nearly 700 different screens during its USA theatrical run earning nearly $5M in box office receipts. With the participation of additional executive producers, Aglialoro continued the trilogy by producing Atlas Shrugged: Part II which debuted in October 2012 on nearly 1200 screens. The third and final part of the novel was produced and written by Aglialoro under the title: Atlas Shrugged Part III: Who Is John Galt?, which debuted on September 12, 2014, in more than 200 theaters. All three films were critically panned. Nevertheless, Aglialoro received awards for the movies including a Saturn Award, an award from the Ronald Reagan Presidential Foundation, Anthem Film Festival and others. Following the theatrical release of the Atlas Shrugged Trilogy, Aglialoro has been approached by a number of producers interested in partnering with him on a remake as a feature or multi-part feature including twice Academy Award Winner (Best Picture – Godfather; Best Picture – Million Dollar Baby), Albert S. Ruddy.