Although he enrolled in a cancer vaccine study in an attempt to ward off the disease, Wayne died of stomach cancer on June 11, 1979, at the UCLA Medical Center. He was buried in the Pacific View Memorial Park Cemetery in Corona del Mar, Newport Beach. According to his son Patrick and his grandson Matthew Muñoz, who was a priest in the California Diocese of Orange, Wayne converted to Roman Catholicism shortly before his death. He requested that his tombstone read "Feo, Fuerte y Formal", a Spanish epitaph Wayne described as meaning "ugly, strong, and dignified". His grave, which was unmarked for 20 years, has been marked since 1999 with the quotation:
Wayne's enduring status as an iconic American was formally recognized by the U.S. government in the form of the two highest civilian decorations. On his 72nd birthday on May 26, 1979, Wayne was awarded the Congressional Gold Medal. Hollywood figures and American leaders from across the political spectrum, including Maureen O'Hara, Elizabeth Taylor, Frank Sinatra, Mike Frankovich, Katharine Hepburn, General and Mrs. Omar Bradley, Gregory Peck, Robert Stack, James Arness, and Kirk Douglas, testified to Congress in support of the award. Robert Aldrich, president of the Directors Guild of America, made a particularly notable statement: