Stryker, who is openly gay, is one of the world's leading philanthropic donors to the LGBT community. His Arcus Foundation is the top LGBT-specific grant-making organization in the United States, giving more than $17 million a year to organizations working toward social justice for LGBT people in 2013.
Stryker is one of the leading funders of great ape conservation efforts around the world. Through the Arcus Foundation, Stryker gave more than $10 million in 2013 to support great ape conservation efforts.
Stryker maintains a home in Garrison, New York, along the Hudson River. In June 2013, Stryker purchased the 129-acre property and placed it under a conservation easement to protect against any future development of the riverfront land. The property's parking area and extensive network of trails, including on-foot access to the Hudson River, is managed by the Open Space Institute and is open to the public, with the exception of a 21-acre residential area.