Holiday was drafted 17th overall by the Philadelphia 76ers in the 2009 NBA draft. On April 3, 2010, he scored a season-high 25 points against the Toronto Raptors. On November 5, 2010, he set a new career high with 29 points against the Cleveland Cavaliers. On February 2, 2011, he recorded his first career triple-double with 11 points, 10 rebounds and 11 assists against the New Jersey Nets. On March 17, 2012, he set a new career high with 30 points against the Chicago Bulls. On November 25, 2012, he set a new career high with 33 points against the Phoenix Suns. On January 2, 2013, he recorded his second career triple-double with 16 points, 10 rebounds and 10 assists against the Suns. On January 18, 2013, he matched his career high with 33 points against the Toronto Raptors. On January 26, 2013, he scored a career-high 35 points against the New York Knicks. Two days earlier, he was selected as a reserve for the Eastern Conference All-Star team for the 2013 NBA All-Star Game. With his first All-Star selection, the 22-year-old Holiday became the youngest player in franchise history to be named an All-Star.