During a game against the Oakland Athletics on April 19, 2015, Herrera was ejected for throwing a pitch behind Brett Lawrie. One game prior to this incident, his teammate Yordano Ventura was also ejected for hitting Lawrie. On April 22, 2015, Herrera was suspended for five games. Herrera appealed the suspension. On April 25, 2015, Herrera was suspended an additional two games for his role in a brawl against the Chicago White Sox. His four-seam fastball had the third-highest average speed of any MLB pitcher's pitches in 2015, at 98.4 mph. Herrera, with the absence of Greg Holland in the 2015 postseason, became the eighth inning set-up man for the Royals. At the conclusion of the postseason, Herrera notched a 0.66 ERA with 22 strikeouts in 13 ⁄3 innings pitched with three holds.