In April 2009, Kardashian and her sister Kourtney announced that they were contracted to star in a spin-off that would follow their move to launch a D-A-S-H store in Miami, Florida. The series, Kourtney and Khloé Take Miami, debuted on E! on August 16, 2009. Starting May 29, 2009, Kardashian joined Miami Top 40 Mainstream outlet WHYI for a weekly four-hour talk/entertainment program, co-hosted by 106 & Park 's Terrence J. Khloé and her sisters Kim and Kourtney made a cameo appearance in the Season 3 premiere of the series 90210. Kardashian made an appearance in episodes 2, 4, and 8 of Kourtney and Kim Take New York, which premiered in January 2011. On April 10, 2011, Khloé & Lamar, Khloé's own show with her husband, Lamar Odom, debuted.
Kardashian participated in the second season of The Celebrity Apprentice, finishing 10th of 16 candidates by being fired by Donald Trump. It was reported she was fired because of her previous arrest for a DUI. In June 2009, Khloé and her sisters teamed up with the Natural Products Association to create a teeth whitening pen called Idol White. Kardashian appeared in one of PETA's "I'd Rather Go Naked Than Wear Fur" campaigns. The three sisters released a jewelry line in March 2010. In the spring of 2010, the sisters released a clothing line for Bebe. Bebe announced they were dropping the line in December 2010. In September 2010, Kardashian and her sisters released another clothing line, K-Dash on QVC. Kardashian and her sisters marketed a fake tan product, released in 2010 and called Kardashian Glamour Tan.