She is survived by her husband, fellow NASA flight surgeon Dr. Jonathan Clark (who was part of an official NASA panel that prepared the final 400-page report about the Space Shuttle Columbia disaster), and son, Iain, who was born in 1996.
Selected by NASA in April 1996, Clark reported to the Johnson Space Center in Houston, Texas in August 1996. After completing two years of training and evaluation, she was qualified for flight assignment as a mission specialist. From July 1997 to August 2000 Clark worked in the Astronaut Office Payloads/Habitability Branch. Clark flew aboard STS-107, logging 15 days, 22 hours and 21 minutes in space.