Jackson grew up in Albury, where she attended Murray High School. She earned her Higher School Certificate in Canberra while she was training with the Australian Institute of Sport. Jackson studied for a psychology degree at Lomonosov Moscow State University and continued via correspondence from America. In 2007, she was working on a university course in business management.
In 2007, Jackson played in the Women's Korean Basketball League and was named the league's Most Valuable Player. She played for Samsung Bichumi (Samsung Insurance) in Seoul, South Korea. Her stint with the team was only four months, and she was the only international player on the team. She averaged 30.2 points per game. No one else on the team spoke English. Jackson claimed this allowed her to play drama free basketball. In a game with Samsung Bichumi against the Kumho Redwings, she scored 56 to set a league record in her team's 96–76 victory. This was a personal best for her in her career. Two weeks prior to the 56-point record, she scored 47 points in a single game. She competed in the league's all star game and was declared the Most Valuable Player of the match. She played two games a week with the league.
Jackson has played club basketball in Europe. She first signed with a European side at the end of the 2005 WNBA season, and went to Russia on a lucrative contract. In 2007, she was paid six figures in American dollars, four times her WNBA base salary, to play with WBC Spartak Moscow Region for one month. Her teammates included other international basketball Olympians: Sue Bird, Diana Taurasi, and Tina Thompson. While playing for the team, she lived in a mansion owned by the team's owner with a view of a nuclear power plant. As a member of the team, she helped Spartak win the 2007 Russian Superleague title. Subsequently, she continued playing for Spartak and won two more Russian Superleague titles with the team, in 2008 and 2009. She scored 35 points in a EuroLeague Women 2008 in an 11 April 2008 game against UMMC Ekaterinburg while playing for Spartak. This was the highest number of points that she scored in a single game in a Euroleague game. Later on, Jackson played for Spartak in the EuroLeague Women finals in Brno, which her team won. She finished the 2008 season with an average of 23.6 points per game and 7.1 rebounds per game.
Jackson was a WNBA All Star for the sixth time in 2007. On 24 July 2007, she scored 47 points in a game against Washington and set a league high single game scoring total that she currently shares. In 2007, she was named the WNBA Defensive Player of the Year. She was also named to the 2007 All-WNBA First Team. She averaged 23.8 points per game, the most points she had averaged per game for a season in the WNBA. She was also named the league's Most Valuable Player. In voting, she received 473 points, with her nearest vote-getting competitor, Becky Hammon, getting only 254. In 2007, she became the first WNBA player to score 4,000 total points the youngest player, as well as the fastest woman to reach the milestone; being named the league MVP gave her a $18,238 bonus and a Tiffany & Co. designed trophy.
Jackson played in 31 games in 2007. She averaged 32.9 minutes per game. Her field goal percentage was 51.9%. She averaged 22.4 points, 2.16 blocks, and 9.3 rebounds per game at the time of the All-Star Break, leading the league in points and blocks, and was second for rebounds. At the All-Star break, she had a three-point shooting percentage of 40.5%. At the end of the season, she expressed an interest in ending her WNBA career with the Storm as she could not see herself playing elsewhere. Her three-point field goal percentage was 40.2%. She had a free throw shooting percentage of 88.3%. She averaged 2.0 blocks per game. She made 258 field goals, ranking second in the league in this category. She ranked third in the league with 497 field goal attempts. She ranked third in the league, with a field goal percentage of 51.9%. She ranked first in the league in defensive rebounds, with 220, for total rebounds, with 300, and for total average number of rebounds per game, with 9.7.