On 29 June 2008, while in Sharm el-Sheikh, Egypt, for an African Union summit, Mwanawasa was hospitalised due to a second stroke. On 1 July, International SOS evacuated him by air ambulance to France for further treatment. The head of the Egyptian hospital to which Mwanawasa was taken said that the doctors there had stopped the brain haemorrhage and that he was in a semi-comatose state. Vice-President Banda said that his condition was stable, and Minister of Information Mike Mulongoti noted that Mwanawasa had previously suffered from hypertension; Mulongoti also said that Mwanawasa was a "very hard working man" and said that this may have been a factor.
On 3 July 2008 news outlets began reporting that Mwanawasa had died in a Paris hospital due to his stroke. The story originated at the Johannesburg-based 702 Talk Radio, which cited Malone Zaza, who claimed to be the head of protocol at Zambia's High Commission in Pretoria, South Africa; however, the commission denied having someone employed at the embassy with that name. Mulongoti, speaking for the government, said the news of Mwanawasa's death was "false," and he urged the South African media to show more restraint in its reporting. As the reports were spreading, South African President Thabo Mbeki called for a moment of silence in Mwanawasa's memory; the South African government quickly expressed regret over this misunderstanding and expressed Mbeki's hopes for Mwanawasa's recovery.
Mwanawasa was hospitalised at the Percy Military Hospital, near Paris. In a statement on 7 July 2008, Banda said that Mwanawasa "remain[ed] in a stable condition" but had to undergo surgery, which Banda described as minor, to correct a breathing problem. Banda said on 8 July that this operation was successful. On 11 July, Banda said that Mwanawasa's condition was stable and that his doctors were "satisfied with [his] current status".