In 2013, she starred in the German tragicomedy Zurich (original title Und morgen Mittag bin ich tot). She received wide critical acclaim for her performance as Lea, a young woman with cystic fibrosis. According to Fries, she prepared for the role by meeting with a patient with the disease, in addition to running up stairs while breathing through a straw. For her role, she was awarded the Bavarian Film Prize 2013, the Max Ophüls Prize, a German Film Critics Award, and the German Director's Prize.