Sonza began singing at a Gaucho folklore community centre in her hometown at the age of 7. She was hired as a child singer by music group Sol Maior, staying with them for 10 years. Sonza would appear in a total of up to 24 concerts a month, with approximately 5 thousand attending each time. In 2014, she launched a cover song YouTube channel, which made her gain online visibility. She became known then as ‘Queen of Covers’.

In August 2016, youtuber Whindersson Nunes asked Luisa to be his girlfriend. In March 2017, they got engaged. In February 2018, they married in a civil and religious ceremony for 350 guests in Alagoas, Brazil.

Sonza signed with Universal Music in May 2017, with her first single, Good Vibes, being then released. In July, she released her second single, Olhos castanhos (Brown Eyes), a song she wrote for then-husband Whindersson Nunes. In October the same year, she released her first, self-titled EP with track Não preciso de você pra nada (There Is Nothing I Need You For) featuring Brazilian singer Luan Santana.

In January 2018, Sonza released the song Rebolar (Twerking) from her first EP as a single. The video peaked 1st on YouTube. In March, Rebolar (Remix) with 5 remix tracks of the song was released as an EP.

In June 2018, Sonza made a special guest appearance in an episode of Brazilian TV sitcom Dra. Darci (Dr Darci), in which she played Julinha. In July, she released Devagarinho (Step by Step), which made it to Spotify’s Brazil Top 50 chart.

In October 2018, Sonza was invited by soap opera writer Aguinaldo Silva to record Nunca foi sorte (It Was Never by Chance), a song written by Silva, for the soundtrack of Rede Globo’s telenovela O sétimo guardião (The Seventh Guardian). She also made a special guest appearance in one of the episodes. Later that year, Sonza released the song as a single and music video.

In November 2018, Sonza released the single Boa menina (Good Girl). In February 2019, a forró version of the song was used in a video featuring Whindersson Nunes. In March 2019, she released Pior que possa imaginar (Worse Than You Can Imagine). Later that year, Sonza released her first album, Pandora.

In June 2020, Sonza gave a performance in the online version of the NYC Pride March.

In September 2020, after protests by Anitta and Sonza, Oxford Languages decided to reassess the definitions of Portuguese words patroa (‘owner’ or ‘boss’, in the feminine gender), professora (‘teacher’, in the feminine gender) and mulher solteira (‘single woman’) appearing in Google’s definitional search, which until then were related to misogynistic definitions such as ‘housewife’ (patroa) and ‘prostitute’ (professora and mulher solteira). Both Google and Oxford Languages issued press releases stating that they would either revise the definitions or remove the item if it ‘no longer reflected the modern usage of Portuguese language by Brazilian speakers.’

In September 2020, news surfaced that Sonza had been accused of racism and was being sued by Black Brazilian lawyer Isabel Macedo who pressed charges for allegedly being tapped in the back by Sonza during a performance in Fernando de Noronha in September 2018, at which point Sonza would have requested Macedo to ‘go grab me a drink’ and later expressed surprise at Macedo’s not being an employee at the restaurant, as well as refused to answer why she assumed Macedo was an employee. Sonza has denied the accusation by saying it’s a ‘lie’ and said she and her legal team would be taking legal action against Macedo.