Bhupathi broke up his partnership with Knowles and began playing once again with Max Mirnyi, with whom he played to win the 2002 US Open. In 2011, Bhupathi reunited with former playing partner Leander Paes for the 2011 Australian Open. The team reached the final, but lost 3–6, 4–6 to the Bryan brothers.On 7 June 2012, Bhupathi and Sania Mirza won the French Open mixed doubles. On 4 November 2012, Bhupathi and partner Rohan Bopanna won the Paris Masters cup. In spite of suffering a setback with their loss against Jonathan Marray and Frederik Nielsen in the ATP Tour Finals opener, the Indian duo reached the final round of the ATP Tour Finals, but suffered a defeat at the hands of Marcel Granollers and Marc López.
Bhupathi appeared with Paes in six season finales. In 2011, they appeared, for the first time since 2002, after securing qualification in mid-October.
On 1 August 2011, Dutta confirmed that she was pregnant with their first child. Their daughter Saira was born on 20 January 2012. In 2010, the couple started a film production company, Big Daddy Productions.