In 2001 Broussard was part of Y, a Christian band based out of New Iberia, Louisiana.

Broussard’s solo career started with the release of several independent efforts, including 2002’s Momentary Setback which spawned “The Wanderer”, a song about self-discovery. A re-worked version of the song appears on his first major album Carencro (Island Records), released on August 3, 2004. The album’s title pays tribute to the musician’s hometown of Carencro, Louisiana, where he still resides. It featured the two singles “Where You Are” (which garnered some considerable airplay on VH1) and “Home”.

Broussard is involved in philanthropic work. He founded the Momentary Setback Fund to benefit victims of Hurricane Katrina and Hurricane Rita. He released an album Bootleg to Benefit the Victims of Hurricane Katrina in 2005, with all proceeds going to help rebuild Broussard’s home state, Louisiana. He is also involved in the United Way and Habitat for Humanity. In 2007, Broussard was involved in an Entertain the Troops tour in the Middle East.

Broussard has been a featured performer on many TV programs including The Tonight Show with Jay Leno, A&E Breakfast with the Arts, Jimmy Kimmel Live!, Late Night with Conan O’Brien, CBS Saturday Early Show, Larry King Live, Lopez Tonight, and CBS’s Saturday Morning’s Second Cup Cafe. His music has been featured on shows such as Clash of the Choirs in which “Home” was performed by a Blake Shelton-led choir. Singer Kelly Clarkson performed “Home” as part of her live setlist in 2006 and 2007. His song “Must Be the Water” was the theme song for the 2008 NBA All-Star Game.

In 2007, he released S.O.S.: Save Our Soul, an album consisting almost entirely of cover songs. The album was his first to reach the top 100 of the Billboard 200 in the US, debuting and peaking at No. 96: this had the effect of “graduating” him from the Top Heatseekers chart, which consists of albums by artists who have never reached the top 100.

Broussard finished recording the Must Be The Water EP on the Rock Boat VII in January 2008 and released it later that year. He was no stranger to the Rock Boat, an annual oceanliner cruise and music festival. This was Broussard’s first release with his new label, Atlantic Records, with which he signed a multi-album contract in 2007.

In 2008, Broussard released his next studio album, Keep Coming Back. The song “Hard Knocks” from this album was featured in the last episode of the 2009 season of the HBO series Hard Knocks which features the Cincinnati Bengals football team.

Broussard married his wife, Sonya, on The Rock Boat VII in January 2008. They have four children.

Broussard’s fourth full-length album, Marc Broussard was released on June 14, 2011. An early EP release, Marc Broussard EP, was released on March 22, 2011, and features the singles “Lucky” and “Only Everything”. A third single, “Cruel”, followed later that year. In late 2012, he signed a deal with Vanguard Records.

On November 6, 2015, he released independently a Christmas album, Magnolias and Mistletoe, which was preceded by the single “Almost Christmas”.

In March 2016, he announced a new studio album which would serve as a sequel to his ’70s-influenced S.O.S.: Save Our Soul cover album. Its first single “Cry to Me” premiered in May. The following year, he released his next studio album Easy to Love on September 15, 2017. In September 2018, he premiered a music video for the song “Memory of You”.