In February 2013, Mengoni competed in the 63rd Sanremo Music Festival with the songs "L'essenziale" and "Bellissimo", the latter written by Gianna Nannini. On 12 February 2013, "L'essenziale" won against "Bellissimo" as the song to be performed by Mengoni during the next stages of the competition. During the fourth night, he also performed a cover of Luigi Tenco's "Ciao amore ciao". On 16 February 2013, Mengoni was announced the winner of the competition. During the same night, an internal jury also chose Mengoni among the other participants to the competition as the Italian entry in the Eurovision Song Contest 2013.
A shortened version of "L'essenziale" was later chosen as the song to be performed during the Eurovision Song Contest. As part of the "Big Five", Mengoni automatically qualified for the final of the competition, held in Malmö, Sweden, on 18 May 2013. Mengoni finished seventh in a field of 26, receiving 126 points.
After being released as a single, "L'essenziale" debuted at number one on the Italian Digital Downloads chart, holding the top spot for a total of eight consecutive weeks and being certified multi-platinum. Both "L'essenziale" and "Bellissimo" were included in Mengoni's second studio album, #prontoacorrere, produced by Michele Canova and released in Italy on 19 March 2013. The album, which features songs written by artists such as Mark Owen, Gianna Nannini, Ivano Fossati and Cesare Cremonini, debuted at number one in Italy, and it was certified platinum by the Federation of the Italian Music Industry. The following singles from the album, "Pronto a correre" and "Non passerai", were released in Italy on 19 April and on 23 August 2013, respectively, and they both entered the top-ten in Mengoni's home country.