Lorphelin attended the College Bréart, and the Lycée Lamartine in Mâcon, named after the famous French poet and politician hailing from Mâcon, Alphonse de Lamartine. Her hobbies are painting, art and fashion. She graduated with highest honors in 2011 from high school with a focus on science and was admitted to the Universite Claude Bernard, Lyon 1’s school of medicine.

Miss Bourgogne 2012 title winner, Marine Lorphelin was crowned Miss France 2013 by the winner of the previous year Delphine Wespiser (Miss France 2012) at the grand finale of the 66th edition of Miss France beauty pageant at the Zenith in Limoges on Grand coronation night of Saturday 8 December 2012.

As Miss France, Marine Lorphelin has promoted two causes: children’s health and the donation of organs. She has signed documents expressing her wish for her organs to be donated post-mortem to those in need, has run in the 2013 Paris Marathon, and has performed numerous dangerous tasks in the Fort Boyard programme to raise 18,000 euros for Mecenat Chirurgie Cardiaque, a French charity that raises money for the heart transplants of children suffering from heart disease. To achieve this, she had to perform tasks as difficult as a bungee jump, riding a bicycle underwater, and diving in ice-cold water to uncover clues about the prize. She participated in the programme for the second time in June 2014.

In 2018, Lorphelin is in her first year of family medicine residency in Paris.