Ramírez was born on 4 July 1954 in Zipaquira, Colombia to Álvaro Ramírez Suárez and Alba Blanco Venturoli, the eldest and only daughter of their four children. In 1974 she married Álvaro Rincón, a Colombian architect; together they have one daughter, María Alejandra. She is of Italian descent through her mother, and thorough her father, she is related to Jesús Ramírez Suárez, her uncle, who served as Chamber Representative for Cundinamarca.